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Alzheimer's Disease (AD)
Alias:
Alzheimer Disease
|
Familial Alzheimer Disease
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Primary Senile Degenerative Dementia
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Alzheimer Disease, Susceptibility to
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Dementia Due to Alzheimer's Disease
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Alzheimer's Disease Pathway Kegg
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Presenile and Senile Dementia
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Alzheimer Disease Type 1
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Alzheimer-Type Dementia
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Alzheimers Dementia
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Alzheimer Sclerosis
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Alzheimer Dementia
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Alzheimer Syndrome
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Alzheimers Disease
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Alzheimers
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Sdat
|
Dat
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Ad
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Alzheimer's disease is a neurodegenerative disorder that is the most common cause of dementia in older adults. It involves memory loss, confusion, and changes in behavior and personality. The disease progresses slowly over many years, affecting brain functions such as memory, language, and decision-making. Alzheimer's can lead to severe mental decline, dependency on others for care, and ultimately death. Risk factors include age, genetics, and lifestyle choices. While there is no cure, treatments are available to manage symptoms and improve quality of life.
Related ID:
Basic Information
Inheritance | Age of Onset | Prevalence | Related Genes | Related Mouse Models | Reference | MALACARDS |
|---|---|---|---|---|---|---|
Ot Other | Unknown | -- | 668 | 6022 | 111 |
Medical Symptom
Phenotype Information Associated with the Current Disease:
Categorization: Anatomical classification of the disease manifestations.
HPO Frequency/Orphanet Frequency: Indicates the probability of the manifestation occurring in the current disease, allowing sorting by probability.
HPO Source Accession: Links to HPO for detailed manifestation information.
Data Source: HPO, Orphanet
Gene & Mutation
Genes and Mutations Associated with the Current Disease:
Function: Primary biological roles of the genes.
Score: Indicates the strength of the association between the disease and the gene, with higher scores reflecting stronger associations.
Count: Number of mutations associated with the disease-gene pair. The number in parentheses represents the total data points linked to the same ClinVar ID. Clicking the number reveals mutation details.
Data Source: Clinvar
Related Drugs
Drugs Related to the Current Gene, Displaying CAS Number, Status and Phase.
Data Source: Clinical Trials
Related Mouse Models
Mouse Models Related to the Current Gene. Click on the model name to view detailed information.
Data Source: MGI, Cyagen
References Literature
Most Relevant Literature for the Current Gene, Filterable by Year, Article Type, and Sortable by Impact Factor.
Data Source: UniProt, PubMed