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Epilepsy
Alias:
Epilepsy Syndrome
|
Epilepsy Due to Genetic Syndromes with Widespread or Progressive Effects
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Epilepsy Due to Unspecified Structural or Metabolic Condition or Disease
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Epilepsy Due to Multiple Sclerosis or Other Demyelinating Disorders
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Epilepsy Due to Other Structural or Metabolic Condition or Disease
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Epilepsy Due to Central Nervous System Infections or Infestations
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Epilepsy Due to Unspecified Prenatal or Perinatal Brain Insults
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Epilepsy Due to Structural or Metabolic Conditions or Diseases
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Epilepsy Due to Other Prenatal or Perinatal Brain Insults
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Epilepsy Due to Neonatal Hypoxic Ischemic Encephalopathy
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Epilepsy Due to Prenatal or Perinatal Vascular Insults
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Epilepsy Due to Prenatal or Perinatal Brain Insults
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Epilepsy Due to Abnormalities of Brain Development
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Epilepsy Due to Tumours of the Nervous System
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Epilepsy Due to Degenerative Brain Disorders
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Epilepsy Due to Neuronal Migration Disorders
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Epilepsy Due to Cerebrovascular Disorders
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Epilepsy with Mesial Temporal Sclerosis
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Epilepsy Due to Hippocampal Sclerosis
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Epilepsy Due to Injuries to the Head
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Epilepsy with Ammon's Horn Sclerosis
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Epilepsy Due to Cortical Dysplasia
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Epilepsy Due to Immune Disorders
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Epilepsy Due to Dementias
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Post Traumatic Epilepsy
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Symptomatic Epilepsies
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Traumatic Epileptic
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Epileptic Syndrome
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Traumatic Epilepsy
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Epilepsies
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures resulting from abnormal electrical activity in the brain. Seizures can vary in symptoms from brief lapses of awareness to convulsions. The condition can be diagnosed after at least two unprovoked seizures occurring more than 24 hours apart, or even after a single seizure if there is a high risk of recurrence. Causes of epilepsy include genetic factors, brain injury, infections, or brain tumors. Treatment involves anti-seizure medications, lifestyle changes, and sometimes surgical interventions. Medication can help control seizures for most individuals, but about 3 out of 10 people may still experience regular seizures. Epilepsy can affect individuals of any age, with symptoms varying among individuals and potentially leading to loss of consciousness or uncontrollable movements. Seizures may be triggered by factors such as structural or metabolic conditions, strokes, brain disorders, or traumatic brain injuries. Additionally, epilepsy can be associated with degenerative brain disorders, CNS infections, intracranial tumors, mesial temporal sclerosis, immunological disorders, disorders of cortical development, or genetically determined conditions.
Related ID:
MALACARDS: EPL164
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MESH: D004827
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ICD11: 1007173668
Basic Information
Inheritance
Age of Onset
Prevalence
Related Genes
Related Mouse Models
Reference
MALACARDS
Ot
Other
Unknown
--
4116
29201
17
EPL164
Medical Symptom
Phenotype Information Associated with the Current Disease:
Categorization: Anatomical classification of the disease manifestations.
HPO Frequency/Orphanet Frequency: Indicates the probability of the manifestation occurring in the current disease, allowing sorting by probability.
HPO Source Accession: Links to HPO for detailed manifestation information.
Data Source: HPO, Orphanet
Gene & Mutation
Genes and Mutations Associated with the Current Disease:
Function: Primary biological roles of the genes.
Score: Indicates the strength of the association between the disease and the gene, with higher scores reflecting stronger associations.
Count: Number of mutations associated with the disease-gene pair. The number in parentheses represents the total data points linked to the same ClinVar ID. Clicking the number reveals mutation details.
Data Source: Clinvar
Related Drugs
Drugs Related to the Current Gene, Displaying CAS Number, Status and Phase.
Data Source: Clinical Trials
Related Mouse Models
Mouse Models Related to the Current Gene. Click on the model name to view detailed information.
Data Source: MGI, Cyagen
References Literature
Most Relevant Literature for the Current Gene, Filterable by Year, Article Type, and Sortable by Impact Factor.
Data Source: UniProt, PubMed
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