Bioinfo Tools
Antibody Discovery
Learn
Contact
EN
中文
Myeloma, Multiple (MM)
Alias:
Multiple Myeloma
|
Medullary Plasmacytoma
|
Myeloma
|
Plasma Cell Myeloma
|
Kahler Disease
|
Myelomatosis
|
Plasma Cell Dyscrasia
|
Kahler's Disease
|
Mm
|
Multiple Myeloma, Susceptibility to, Somatic Mutation
|
Multiple Myeloma, Resistance to, Somatic Mutation
|
Multiple Myeloma Without Mention of Remission
|
Multiple Myeloma/plasma Cell Myeloma
|
Immunoglobulin Deposition Disease
|
Myeloid Neoplasm of Plasma Cell
|
Myeloma, Plasma Cell, Malignant
|
Monostotic Plasma Cell Myeloma
|
Primary Systemic Amyloidosis
|
Plasma Cell Myeloid Neoplasm
|
Kahler-Bozzolo Disease
|
Plasma Cell Neoplasm
|
Plasma Cell Myelomas
|
Multiple Myeloma Nos
|
Primary Amyloidosis
|
Plasmacytic Myeloma
|
Multiple Myelomata
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Multiple myeloma is a cancer of plasma cells in the bone marrow, characterized by abnormal cell growth leading to tumors in bones, bone pain, fractures, weakness, and fatigue. Symptoms may include frequent infections, thirst, and urination. Diagnosis involves lab tests and imaging, with treatment options such as chemotherapy, stem cell transplantation, radiation, or targeted therapy. The disorder can cause anemia, weakened immune system, kidney problems, and hypercalcemia. It is more common in older individuals, African Americans, and those with a family history of the condition.
Related ID:
Basic Information
Inheritance | Age of Onset | Prevalence | Related Genes | Related Mouse Models | Reference | MALACARDS |
|---|---|---|---|---|---|---|
Ot Other | Adult | 1-9/100000 Prevalence at birth: 1-9/100000 (United States) Annual incidence: 1-9/100000 (Worldwide, France, Europe, United States, Iran, Islamic Republic of, Australia, Denmark) Point prevalence: 1-5/10000 (Europe) | 662 | 6182 | 63 |
Medical Symptom
Phenotype Information Associated with the Current Disease:
Categorization: Anatomical classification of the disease manifestations.
HPO Frequency/Orphanet Frequency: Indicates the probability of the manifestation occurring in the current disease, allowing sorting by probability.
HPO Source Accession: Links to HPO for detailed manifestation information.
Data Source: HPO, Orphanet
Gene & Mutation
Genes and Mutations Associated with the Current Disease:
Function: Primary biological roles of the genes.
Score: Indicates the strength of the association between the disease and the gene, with higher scores reflecting stronger associations.
Count: Number of mutations associated with the disease-gene pair. The number in parentheses represents the total data points linked to the same ClinVar ID. Clicking the number reveals mutation details.
Data Source: Clinvar
Related Drugs
Drugs Related to the Current Gene, Displaying CAS Number, Status and Phase.
Data Source: Clinical Trials
Related Mouse Models
Mouse Models Related to the Current Gene. Click on the model name to view detailed information.
Data Source: MGI, Cyagen
References Literature
Most Relevant Literature for the Current Gene, Filterable by Year, Article Type, and Sortable by Impact Factor.
Data Source: UniProt, PubMed