CyageniCyagen
HomeAI Assistant
Toolbox
Databases
Resources
About Us
AI Tools
RNA Splicer
ASO Designer
Pathogenicity Predictor
Bioinfo Tools
Sequence Viewer
Mutation Direct
Antibody Discovery
Target Insights
Computational Analysis
Databases
Gene Database
Disease Database
Model Database
Mutation Database
Learn
Learning Center
Explore
iCyagen
Cyagen
OriCellTM
AbSeekTM
Contact
Contact Us
EN
中文
Semantic Dementia
Alias:
Semantic Variant Ppa
|
Dementia, Frontotemporal, with or Without Parkinsonism
|
Semantic Primary Progressive Aphasia
|
Semantic Variant of Primary Progressive Aphasia
|
Dementia, Frontotemporal
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Semantic dementia is a form of frontotemporal dementia characterized by the progressive loss of semantic knowledge and behavioral abnormalities due to degeneration of the anterior temporal lobes. It is also known as semantic variant primary progressive aphasia and results in a loss of semantic memory in both verbal and non-verbal domains, with common symptoms being a loss of word meaning. Patients with this disorder may struggle to match words or images to their meanings, and while category-specific impairments are rare, a generalized semantic impairment typically occurs.
Related ID:
MALACARDS: SMN008
|
ICD11: 831337417
Basic Information
Inheritance
Age of Onset
Prevalence
Related Genes
Related Mouse Models
Reference
MALACARDS
Ot
Other
Adult
--
55
741
332
SMN008
Medical Symptom
Phenotype Information Associated with the Current Disease:
Categorization: Anatomical classification of the disease manifestations.
HPO Frequency/Orphanet Frequency: Indicates the probability of the manifestation occurring in the current disease, allowing sorting by probability.
HPO Source Accession: Links to HPO for detailed manifestation information.
Data Source: HPO, Orphanet
Gene & Mutation
Genes and Mutations Associated with the Current Disease:
Function: Primary biological roles of the genes.
Score: Indicates the strength of the association between the disease and the gene, with higher scores reflecting stronger associations.
Count: Number of mutations associated with the disease-gene pair. The number in parentheses represents the total data points linked to the same ClinVar ID. Clicking the number reveals mutation details.
Data Source: Clinvar
Related Drugs
Drugs Related to the Current Gene, Displaying CAS Number, Status and Phase.
Data Source: Clinical Trials
Related Mouse Models
Mouse Models Related to the Current Gene. Click on the model name to view detailed information.
Data Source: MGI, Cyagen
References Literature
Most Relevant Literature for the Current Gene, Filterable by Year, Article Type, and Sortable by Impact Factor.
Data Source: UniProt, PubMed
Cyagen
Home
Tools
Database
Resources
About Us
Email: icyagen-support@cyagen.com
Phone: +86 18620792549
Address: No.98, Xiangxue Road, Huangpu District, Guangzhou City
Follow us on social media
Contact us via LinkedIn
Link: https://www.linkedin.com/company/cyagen-biosciences
Copy
Contact us via YouTube
Link: https://www.youtube.com/@Cyagen
Copy
iCyagen
Copyright © 2024 Cyagen Biosciences. All Rights Reserved.
Privacy Policy
User Agreement
Back to top