3M syndrome is an autosomal recessive disorder characterized by distinctive facial features, severe prenatal and postnatal growth retardation, and normal intelligence. Skeletal anomalies include long, slender tubular bones, reduced vertebral body diameter, and delayed bone age. Other manifestations are joint hypermobility, joint dislocation, winged scapulae, and pes planus. The disorder is caused by mutations in CUL7, OBSL1, or CCDC8 genes and is inherited in an autosomal recessive pattern. Diagnosis is based on clinical features, and treatment aims to address growth and skeletal issues. Life expectancy is generally normal, and intelligence is unaffected. Individuals with 3M syndrome have a triangle-shaped face with a broad forehead, pointed chin, large ears, full eyebrows, and other facial features. Additional skeletal abnormalities may include a short, broad neck, prominent shoulder blades, square shoulders, spinal curvature, clinodactyly, and loose joints. A variant called Yakut short stature syndrome has been identified in the Yakut population, with additional breathing problems in infancy.